Adenosine Receptor
The adenosine receptors (P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as endogenous ligand. In humans, there are four types of adenosine receptors(A1,A2A ,A2B,A3). Each is encoded by a separate gene and has different functions, although with some overlap. For instance, both A1 receptors and A2A play roles in the heart, regulating myocardial oxygen consumption and coronary blood flow, while the A2A receptor also has broader anti-inflammatory effects throughout the body. These two receptors also have important roles in the brain, regulating the release of other neurotransmitters such as dopamine and glutamate, while the A2B and A3 receptors are located mainly peripherally and are involved in processes such as inflammation and immune responses.
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TC-G 1004是活性选择性 A2A 拮抗剂。
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SL 0101-1是选择性 ribosomal S6 kinase (RSK) 抑制剂。
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SLV 320是活性的，选择性 A1 拮抗剂。
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SDZ WAG 994是活性的， 选择性 A1 激动剂。
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SCH 58261是活性的， 高选择性的A2A拮抗剂。
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